Scanpy MCP server

Scanpy MCP server

By huang-sh GitHub

MCP server for Scanpy

Overview

What is Scanpy MCP?

Scanpy MCP is a server designed for single-cell RNA sequencing (scRNA-Seq) analysis using natural language, built on the Scanpy framework.

How to use Scanpy MCP?

To use Scanpy MCP, install it via PyPI with the command pip install scanpy-mcp, and integrate it into AI clients or agent frameworks that support the MCP protocol.

Key features of Scanpy MCP?

  • Natural language processing for reading and writing scRNA-Seq data.
  • Comprehensive preprocessing capabilities including filtering, quality control, and normalization.
  • Advanced tools for clustering, differential expression, and trajectory inference.
  • Visualization options such as violin plots, heatmaps, and dot plots.

Use cases of Scanpy MCP?

  1. Performing scRNA-Seq analysis using simple natural language commands.
  2. Enabling developers to integrate scRNA-Seq functionalities into their applications.
  3. Facilitating educational demonstrations of scRNA-Seq analysis in AI environments.

FAQ from Scanpy MCP?

  • Can Scanpy MCP handle all types of scRNA-Seq data?

Yes, it is designed to work with various scRNA-Seq datasets and provides flexible analysis options.

  • Is there a demo available for Scanpy MCP?

Yes, a demo showcasing scRNA-Seq cell cluster analysis is available in the documentation.

  • How can I install Scanpy MCP?

You can install it using pip install scanpy-mcp or run it in a Docker container.

Content

Scanpy MCP server

An MCP server for scRNA-Seq analysis software Scanpy with natural language!

🪩 What can it do?

  • IO module like read and write scRNA-Seq data with natural language
  • Preprocessing module,like filtering, quality control, normalization, scaling, highly-variable genes, PCA, Neighbors,...
  • Tool module, like clustering, differential expression etc.
  • Plotting module, like violin, heatmap, dotplot

❓ Who is this for?

  • Anyone who wants to do scRNA-Seq analysis natural language!
  • Agent developers who want to call scanpy's functions for their applications

🌐 Where to use it?

You can use scanpy-mcp in most AI clients, plugins, or agent frameworks that support the MCP:

  • AI clients, like Cherry Studio
  • Plugins, like Cline
  • Agent frameworks, like Agno

🎬 Demo

A demo showing scRNA-Seq cell cluster analysis in a AI client Cherry Studio using natural language based on scanpy-mcp

https://github.com/user-attachments/assets/93a8fcd8-aa38-4875-a147-a5eeff22a559

🏎️ Quickstart

Install

Install from PyPI

pip install scanpy-mcp

you can test it by running

scmcp run

run scnapy-server locally

Refer to the following configuration in your MCP client:

"mcpServers": {
  "scanpy-mcp": {
    "command": "scmcp",
    "args": [
      "run"
    ]
  }
}

run scnapy-server remotely

Refer to the following configuration in your MCP client:

run it in your server

scmcp run --transport sse --port 8000

Then configure your MCP client, like this:

http://localhost:8000/sse

🤝 Contributing

If you have any questions, welcome to submit an issue, or contact me(hsh-me@outlook.com). Contributions to the code are also welcome!

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